Henk Granzier’s research group uses an atomic force microscope sensitive enough to hold onto a single titin protein molecule and measure the tiny forces that occur during stretching and contracting under various conditions. (Photo: Katie Maass/Sarver Heart Center)
$6M Grant Boosts Molecular Heart Research Combining the resources and expertise of seven institutions in North America and Europe, a research program will offer new insights into the molecular workings of heart muscle cells and how genetic mutations affect their function. Henk Granzier, a UA professor of physiology, is one of two principal investigators leading the prestigious and highly competitive project.
UA Boosts HIV Early Intervention Services The UA's Petersen Clinics are working to promote early detection of HIV while connecting newly infected patients with care and services as soon as possible. More than 1.1 million people in the United States are living with HIV, and nearly one in five are unaware of their infection, according to the Centers for Disease Control and Prevention. Early detection and intervention can go a long way in improving patient outcomes and preventing the spread of the virus.
Young Doctor Defies Odds, Plans to Practice in Tucson Michael Lokale overcame a rough childhood to excel in family medicine. He is finishing a residency at the UA and, in July, plans to join a practice in Tucson. To Lokale, being a family doctor means being "a complete doctor. You get to see people when they are born. You deliver them, and you follow them throughout their lives. You form relationships with them. You know their stories. I think that's very cool."
UA Research Determines Feasibility of Newborn Screening in Tucson Research by UA medical student Lucy Han finds that implementing recommended pulse oximetry screening guidelines is feasible at Tucson's elevation. A recent simple pulse oximetry test revealed a potentially life-threatening critical congenital heart defect in a newborn that was surgically repaired at The University of Arizona Medical Center-University Campus.
ALS affects the nerve cells in the brain and spinal cord responsible for movement. The disease causes a loss of muscle function, including the muscles used for speech, swallowing and breathing, and paralysis that eventually leads to death. The mind and senses mostly remain unaffected. Some patients may have cognitive changes, including depression and problems with decision-making and memory.
Seed Funding Leads to Major UA Grants When Tucson judge Jim Himelic died in 2000, his family and friends established a foundation in his honor to raise funds to support ALS research at the UA and elsewhere. UA researchers studying ALS have greatly benefited from the seed money, in some cases subsequently gaining larger grants, and the foundation's major fundraiser this month intends to ensure that such opportunities continue.
Henk Granzier’s research group uses an atomic force microscope sensitive enough to hold onto a single titin protein molecule and measure the tiny forces that occur during stretching and contracting under various conditions. (Photo: Katie Maass/Sarver Heart Center)
ALS affects the nerve cells in the brain and spinal cord responsible for movement. The disease causes a loss of muscle function, including the muscles used for speech, swallowing and breathing, and paralysis that eventually leads to death. The mind and senses mostly remain unaffected. Some patients may have cognitive changes, including depression and problems with decision-making and memory.

UA Researcher Studies Protein's Link to Heart Disease

  • UANews
  • June 17, 2013
The largest protein known to exist in the human body functions as a molecular spring, and the UA's Henk Granzier is gaining new insights into its role in heart disease. Many heart conditions are well-characterized on a clinical level, but our understanding of what causes these conditions on a cellular and molecular level is still extremely limited.

A Father's Search Finds Reason for Daughter's Epilepsy

  • Arizona Daily Star
  • June 17, 2013
The UA's Michael Hammer is an expert in population genomics. He directs the UA's Human Genomics Core, which traced the origins of a half-million people for National Geographic's Genographic project. His lab also found the source of his daughter's epilepsy.

$6M Grant Boosts Molecular Heart Research

  • UANews
  • June 17, 2013
Combining the resources and expertise of seven institutions in North America and Europe, a research program will offer new insights into the molecular workings of heart muscle cells and how genetic mutations affect their function. Henk Granzier, a UA professor of physiology, is one of two principal investigators leading the prestigious and highly competitive project.

UA Boosts HIV Early Intervention Services

  • UANews
  • June 13, 2013
The UA's Petersen Clinics are working to promote early detection of HIV while connecting newly infected patients with care and services as soon as possible. More than 1.1 million people in the United States are living with HIV, and nearly one in five are unaware of their infection, according to the Centers for Disease Control and Prevention. Early detection and intervention can go a long way in improving patient outcomes and preventing the spread of the virus.

Young Doctor Defies Odds, Plans to Practice in Tucson

  • UANews
  • June 11, 2013
Michael Lokale overcame a rough childhood to excel in family medicine. He is finishing a residency at the UA and, in July, plans to join a practice in Tucson. To Lokale, being a family doctor means being "a complete doctor. You get to see people when they are born. You deliver them, and you follow them throughout their lives. You form relationships with them. You know their stories. I think that's very cool."

Brain Parasite Has Potential to Unlock Neurobiology Secrets

  • UANews
  • June 10, 2013
Dr. Anita Koshy sees a common and typically harmless brain parasite as a potential key to unlocking secrets of neurobiology that can be used to intervene in diseases such as Alzheimer's and multiple sclerosis. She has developed new models for the study of Toxoplasma gondii, a parasite that infects more than 10 percent of Americans and up to 80 percent of the population in some countries.

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